About the McGlinn Group
The McGlinn Group aims to elucidate the complex genetic hierarchies that drive patterning and growth of the developing embryo, with particular focus on the vertebrate limb and axial skeleton. A comprehensive understanding of these processes requires integration of all levels of gene regulation, including both protein-coding and non-protein coding mechanisms.
The McGlinn Group draws on the strengths of both the mouse
and chick as
model organisms. The lab has intricate knowledge of mouse
knockout
approaches and combines this with cutting edge knockdown
strategies in
the early mouse embryo facilitated by in utero ultrasound
guided
injection. The Group employs classical embryological
techniques in chick
as well as retroviral methods of gene delivery. Importantly,
Dr McGlinn
has pioneered a novel strategy to knockdown individual
miRNAs in the
developing chick and mouse embryo.
More information on the McGlinn Group can be found at:
www.armi.org.au/Research1/Research_Groups/McGlinn.aspx
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