Contact Details

Szun is interested in T cell immunity to cancer, infection and transplantation. She employs cellular, genetic, flow cytometry and real-time microscopy techniques to identify cues that govern T cell migration and function in vivo. She currently investigates T cell behaviour within lymphoid tissues and the tumour microenvironment.

Highlight publications

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Tay SS, Carol H, Biro M.

TriKEs and BiKEs join CARs on the cancer immunotherapy highway.

Hum Vaccin Immunother. 2016 Jun 20:1-7. [Epub ahead of print]

Roediger B, Kyle R, Tay SS, Mitchell AJ, Bolton HA, Guy TV, Tan SY, Forbes-Blom E, Tong PL, Köller Y, Shklovskaya E, Iwashima M, McCoy KD, Le Gros G, Fazekas de St Groth B, Weninger W.

IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation.

J Allergy Clin Immunol. 2015 Dec;136(6):1653-1663.e7. doi: 10.1016/j.jaci.2015.03.043. Epub 2015 May 27.

Le Couteur DG, Tay SS, Solon-Biet S, Bertolino P, McMahon AC, Cogger VC, Colakoglu F, Warren A, Holmes AJ, Pichaud N, Horan M, Correa C, Melvin RG, Turner N, Ballard JW, Ruohonen K, Raubenheimer D, Simpson SJ.

The Influence of Macronutrients on Splanchnic and Hepatic Lymphocytes in Aging Mice.

J Gerontol A Biol Sci Med Sci. 2015 Dec;70(12):1499-507. doi: 10.1093/gerona/glu196. Epub 2014 Oct 21.

Lisowski L, Tay SS, Alexander IE.

Adeno-associated virus serotypes for gene therapeutics.

Curr Opin Pharmacol. 2015 Oct;24:59-67. doi: 10.1016/j.coph.2015.07.006. Epub 2015 Aug 25.

Wong YC, Tay SS, McCaughan GW, Bowen DG, Bertolino P.

Immune outcomes in the liver: Is CD8 T cell fate determined by the environment?

J Hepatol. 2015 Oct;63(4):1005-14. doi: 10.1016/j.jhep.2015.05.033. Epub 2015 Jun 20.

Tong PL, Roediger B, Kolesnikoff N, Biro M, Tay SS, Jain R, Shaw LE, Grimbaldeston MA, Weninger W.

The skin immune atlas: three-dimensional analysis of cutaneous leukocyte subsets by multiphoton microscopy

J Invest Dermatol. 2015 Jan;135(1):84-93. doi: 10.1038/jid.2014.289. Epub 2014 Aug 9.

Brockhausen J, Tay SS, Grzelak CA, Bertolino P, Bowen DG, d'Avigdor WM, Teoh N, Pok S, Shackel N, Gamble JR, Vadas M, McCaughan GW.

miR-181a mediates TGF-β-induced hepatocyte EMT and is dysregulated in cirrhosis and hepatocellular cancer.

Liver Int. 2015 Jan;35(1):240-53. doi: 10.1111/liv.12517. Epub 2014 Apr 30.

Tay SS, Wong YC, Roediger B, Sierro F, Lu B, McDonald DM, McGuffog CM, Meyer NJ, Alexander IE, Parish IA, Heath WR, Weninger W, Bishop GA, Gamble JR, McCaughan GW, Bertolino P, Bowen DG.

Intrahepatic activation of naive CD4+ T cells by liver-resident phagocytic cells.

J Immunol. 2014 Sep 1;193(5):2087-95. doi: 10.4049/jimmunol.1400037. Epub 2014 Jul 28.

Tay SS, Wong YC, McDonald DM, Wood NA, Roediger B, Sierro F, Mcguffog C, Alexander IE, Bishop GA, Gamble JR, Weninger W, McCaughan GW, Bertolino P, Bowen DG.

Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2540-9. doi: 10.1073/pnas.1406674111. Epub 2014 Jun 10.

Tay SS, Roediger B, Tong PL, Tikoo S, Weninger W.

The Skin-Resident Immune Network.

Curr Dermatol Rep. 2013 Nov 28;3:13-22. eCollection 2014.

Tay SS, Lu B, Sierro F, Benseler V, McGuffog CM, Bishop GA, Cowan PJ, McCaughan GW, Dwyer KM, Bowen DG, Bertolino P.

Differential migration of passenger leukocytes and rapid deletion of naive alloreactive CD8 T cells after mouse liver transplantation.

Liver Transpl. 2013 Nov;19(11):1224-35. doi: 10.1002/lt.23720. Epub 2013 Sep 14.

Roediger B, Kyle R, Yip KH, Sumaria N, Guy TV, Kim BS, Mitchell AJ, Tay SS, Jain R, Forbes-Blom E, Chen X, Tong PL, Bolton HA, Artis D, Paul WE, Fazekas de St Groth B, Grimbaldeston MA, Le Gros G, Weninger W.

Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells.

Nat Immunol. 2013 Jun;14(6):564-73. doi: 10.1038/ni.2584. Epub 2013 Apr 21.

 
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