Szun is interested in T cell immunity to cancer, infection and transplantation. She employs cellular, genetic, flow cytometry and real-time microscopy techniques to identify cues that govern T cell migration and function in vivo. She currently investigates T cell behaviour within lymphoid tissues and the tumour microenvironment.
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Highlight publications
TriKEs and BiKEs join CARs on the cancer immunotherapy highway.
Hum Vaccin Immunother. 2016 Jun 20:1-7. [Epub ahead of print]
IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation.
J Allergy Clin Immunol. 2015 Dec;136(6):1653-1663.e7. doi: 10.1016/j.jaci.2015.03.043. Epub 2015 May 27.
The Influence of Macronutrients on Splanchnic and Hepatic Lymphocytes in Aging Mice.
J Gerontol A Biol Sci Med Sci. 2015 Dec;70(12):1499-507. doi: 10.1093/gerona/glu196. Epub 2014 Oct 21.
Adeno-associated virus serotypes for gene therapeutics.
Curr Opin Pharmacol. 2015 Oct;24:59-67. doi: 10.1016/j.coph.2015.07.006. Epub 2015 Aug 25.
Immune outcomes in the liver: Is CD8 T cell fate determined by the environment?
J Hepatol. 2015 Oct;63(4):1005-14. doi: 10.1016/j.jhep.2015.05.033. Epub 2015 Jun 20.
The skin immune atlas: three-dimensional analysis of cutaneous leukocyte subsets by multiphoton microscopy
J Invest Dermatol. 2015 Jan;135(1):84-93. doi: 10.1038/jid.2014.289. Epub 2014 Aug 9.
miR-181a mediates TGF-β-induced hepatocyte EMT and is dysregulated in cirrhosis and hepatocellular cancer.
Liver Int. 2015 Jan;35(1):240-53. doi: 10.1111/liv.12517. Epub 2014 Apr 30.
Intrahepatic activation of naive CD4+ T cells by liver-resident phagocytic cells.
J Immunol. 2014 Sep 1;193(5):2087-95. doi: 10.4049/jimmunol.1400037. Epub 2014 Jul 28.
Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses.
Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2540-9. doi: 10.1073/pnas.1406674111. Epub 2014 Jun 10.
The Skin-Resident Immune Network.
Curr Dermatol Rep. 2013 Nov 28;3:13-22. eCollection 2014.
Differential migration of passenger leukocytes and rapid deletion of naive alloreactive CD8 T cells after mouse liver transplantation.
Liver Transpl. 2013 Nov;19(11):1224-35. doi: 10.1002/lt.23720. Epub 2013 Sep 14.
Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells.
Nat Immunol. 2013 Jun;14(6):564-73. doi: 10.1038/ni.2584. Epub 2013 Apr 21.