The Davidovich Group aim to understand the detailed molecular events that underlie the recruitment and regulation of chromatin-modifying complexes by their co-factor proteins, RNAs and DNA.

For more information about Dr Davidovich and his work, please visit his website -

  • Recruitment and regulation of chromatin-modifying complexes by their co-factor proteins.

More information about Dr Davidovich is available on his website -

Published In

Wang X, Goodrich KJ, Gooding AR, Naeem H, Archer S, Paucek RD, Youmans DT, Cech TR, Davidovich C.

Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines.

Mol Cell. 2017 Mar 16;65(6):1056-1067.e5. doi: 10.1016/j.molcel.2017.02.003.

Davidovich C, Cech TR.

The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2.

RNA. 2015 Dec;21(12):2007-22. doi: 10.1261/rna.053918.115. PubMed PMID: 26574518; doi: 10.1261/rna.053918.115.

Davidovich C, Wang X, Cifuentes-Rojas C, Goodrich KJ, Gooding AR, Lee JT, Cech TR.

Toward a consensus on the binding specificity and promiscuity of PRC2 for RNA.

Mol Cell. 2015 Feb 5;57(3):552-8. doi: 10.1016/j.molcel.2014.12.017. Epub 2015 Jan 15. PubMed PMID: 25601759; PubMed Central PMCID: PMC4320675.

Davidovich C, Goodrich KJ, Gooding AR, Cech TR.

A dimeric state for PRC2.

Nucleic Acids Res. 2014 Aug;42(14):9236-48. doi: 10.1093/nar/gku540. Epub 2014 Jul 3. PubMed PMID: 24992961; PubMed Central PMCID: PMC4132707.

Davidovich C, Zheng L, Goodrich KJ, Cech TR.

Promiscuous RNA binding by Polycomb repressive complex 2.

Nat Struct Mol Biol. 2013 Nov;20(11):1250-7. doi: 10.1038/nsmb.2679. Epub 2013 Sep 29. PubMed PMID: 24077223; PubMed Central PMCID: PMC3823624.