Maté is spearheading the use of complex in vitro and in vivo models for studying the cell-intrinsic actin cytoskeleton cues and dynamics that govern the invasive migration of tumour cells, the tissue scanning of T cells and their cytotoxic interaction with tumour cells. Using a multidisciplinary approach encompassing cell biology, biophysics, bioimage informatics and advanced light microscopy, he aims to unravel fundamental actin-based processes and develop new methodologies for basic cell biological research. Maté’s research relies heavily on advanced microscopy and the development of image analysis platforms capable of automatically detecting and analysing the kinetics of actomyosin, cell movement and protrusions.
EMBL Australia node in Single Molecule Science
The University of New South Wales
Level 3, Lowy Cancer Research Centre
Sydney, NSW 2052, Australia
Phone: +61 (0) 293 858 020
Fax: +61 (0) 293 851 389
Dr. Maté Biro received his PhD at the Max Planck Institute of Molecular Cell Biology and Genetics in Germany in 2011.
His doctoral work focused on the biophysics of cellular actin cortex assembly. He previously studied Physics (BSc) and then Bioinformatics and Theoretical Systems Biology (MSc) at the Imperial College in London, UK, and did his Masters research at MIT, Cambridge, MA, USA.
He has worked at a particle accelerator in Tsukuba, Japan and as a Research Associate at the Bioinformatics Institute of the A*STAR in Singapore.
In 2012, he moved to Sydney and the Centenary Institute at the University of Sydney, where he initially worked as a postdoc and then as of 2014 as group leader of the Cellular Mechanobiology lab.
Dr. Biro joined EMBL Australia as a group leader at the Single Molecule Science node at UNSW in January 2016.
His research, highly multidisciplinary in nature, focuses on the dynamics and regulation of the actin cytoskeleton, notably during the migration of T cells and tumour cells, and the immunological interactions between them.