Understanding how complex properties arise out of molecules and their interactions, with a primary focus on endosomal trafficking at the level of single cells and in the context of intercellular communications in development.
- Endosomal transport and signal processing
- Advanced fluorescence imaging and spectroscopy (Single Molecule imaging, Lattice Light-Sheet microscopy, Fluroescenc Correlation Spectroscopy, Fluorescence Lifetime, Optogenetics)
- Computational image analysis
- Inter-organelle interactions and integrative processes.
- Cell migration and cellular decision making
- Teaching: evolving undergraduate teaching approaches for modern biochemistry (encompassing quantitative microscopy, modelling and concepts of emergent phenomena)
Dr Senthil Arumugam obtained his PhD training in the lab of Prof Petra Schwille at the Max Planck Institute for Cell Biology and Genetics in Dresden, Germany, focusing on self-organisation of proteins involved in bacterial cell division.
His post-doctoral work in the labs of Prof Patricia Bassereau and Prof Ludger Johannes at the Curie Institute, Paris, France, focused on protein-membrane interactions and cellular trafficking.
Dr Arumugam joined Single Molecule Science at the University of New South Wales as an independent group leader in September 2016 and established the Lattice Light-Sheet Imaging infrastructure with his research focused on endosomal trafficking.
At EMBL Australia at the Monash Biomedicine Discovery Institute, Senthil spearheads an interdisciplinary group focussed on cellular physiology.